Savíns Puertas Martín
PhD in Informatics
Profile
Savíns Puertas Martín is currently on a two-year research stay (2022-20224) in the
Chemoinformatics group at the University of Sheffield, United Kingdom.
He finished his degree in Computer Engineering at the University of Almeria in June
2015, receiving the prizes for the best record of the promotion and the best final
project. In September of the same year, he started the Master's degree in Computer
Engineering at the same university and obtained a Collaboration Scholarship in which he
began working in the area of drug development. During his second year of Master, he
started a PhD in Computer Science funded by a 4-year FPU grant from the Spanish
Ministry, also in Almeria. In June 2017, he finished the Master's degree, obtaining the
best record and the best Master's thesis. He finished his PhD in October 2020 with the
highest qualification, cum laude, and international mention. His research has focused on
the design and development of different drug development techniques. Specifically, a
technique called Virtual Screening, which is normally used as one of the first stages in
the drug development process, reducing the number of compounds to be analysed later,
saving time and money. Among its developments is the OptiPharm software, for which he
has registered its intellectual property (RTA-94-18). OptiPharm software has been sued
by several universities and companies in different countries. It is currently being used
for two projects: one related to COVID-19 with international commercial interests and
another with a European company in which effects have been found that could be relevant
for the treatment of certain medical conditions and which is still in the experimental
phase. In addition to following this line, Savins worked for a year on a radiotherapy
project and, more specifically, on the improvement and automation of the planning of
intensity-modulated radiotherapy (IMRT). He is currently in Sheffield (UK) on a two-year
research stay on virtual screening and molecular flexibility. His teaching activity has
been related to Computer Architecture and Technology, High-Performance Computing and
Computer Networks.
Work Experiance
Post-doctoral Researcher 01.02.2022-now
Chemoinformatics research group. Information School. University of Sheffield, United
Kingdom
- working on Virtual Screening problems and
molecular flexibility.
Post-doctoral Researcher 01.02.2021-31.01.2022
Supercomputing-Algorithm Research Group. Dept. of Informatics, University of Almería
- working on the project High Performance
Computing for Optimizing Intensity Modulated Radiation Therapy Schedules
Pre-doctoral Researcher. National Competitive Scholarship FPU (Formación de Profesorado
Universitario (University Teacher Training)).01.10.2016-30.09.2020
Supercomputing-Algorithm Research Group. Dept. of Informatics, University of Almería
Research Labor Staff 01.06.2016-30.09.2016
Supercomputing-Algorithm Research Group. Dept. of Informatics, University of Almería
Awards and Achievements
VII Research Awards Scientific Computer Society of Spain (SCIE) - BBVA Foundation 2022.
2022
22th November
Third prize in Your PhD Thesis in Three Minutes competition. 2021
Jornadas Sarteco 22-24 September
Official Accreditation.2021
National Agency for Quality Assessment and Accreditation
- Assistant Doctor Professor
- Private University Professor
- Hired Doctor Professor
FPU Scholarship 2016-2020
Spanish Ministry of Education, Culture and Sport
- The FPU scholarship
provides nancial support for awardees to complete an o cial PhD program and
to carry out research and teaching activities, in any discipline, by signing a
predoctoral
contract.
- Code: FPU15/02912.
Best Final project award in Informatics Master 2018
EPS-FCCEE - University of Almería
Best academic record award in Informatics Master 2018
University of Almeria. Informatics
Master.
Collaboration grant with the Department of Informatics of the University of
Almeria, 2016
Spanish Ministry of Education, Culture and Sport
Best nal project award in Informatics Degree2015
EPS-FCCEE - University of Almería
Best academic record award in Informatics Degree 2015
University of Almeria. Informatics Degree.
Education
PhD in Informatics 2016-2020
University of Almería
- Score: Cum laude (maximum score).
International Mention.
- Thesis title: High Performance Computing for
Optimization Problem Solving in Bioinformatics.
Master in Informatics2015-2017
University of Almería
- Average score: 9.79 out 10.
- Final master project title: Solving
optimization problems in the pharmaceutical industry through evolutionary
algorithms.
Degree in Informatics 2011-2015
University of Almería
- Average score: 9.55 out 10.
- Final degree project title: a voice
interaction system for handling mashup interfaces.
Research Publication
Journal Articles
- M. R. Ferrández, S. Puertas-Martín, J. L. Redondo, H. Pérez-Sánchez, and P. M. Ortigosa, “A two-layer
mono-objective algorithm based on guided optimization to reduce the computational cost in virtual
screening,” Scientific Reports, vol. 12, no. 1, p. 12 769, Dec. 2022 , issn: 2045-2322. doi: 10.1038/s41598-022-16913-w. [Online]. Available: https://doi.org/10.1038/s41598-022-16913-w
- S. Puertas-Martín, J. L. Redondo, M. R.
Ferrández, H. Pérez-Sánchez, and P. M. Ortigosa, “MultiPharm-DT: A Multi-Objective
Decision Tool for Ligand-Based Virtual Screening Problems,” Informatica, pp. 1–26,
Dec. 2021, issn: 0868-4952. doi: 10.15388/21-INFOR469. [Online]. Available: https://doi.org/10.15388/21-INFOR469
- S. Puertas-Martín, J. L. Redondo, H.
Pérez-Sánchez, and P. M. Ortigosa, “Optimizing Electrostatic Similarity for Virtual
Screening: A New Methodology,” Informatica, pp. 1–19, Jul. 2020, issn: 0868-4952.
doi: 10.15388/20-INFOR424. [Online]. Available: https://informatica.vu.lt/doi/10.15388/20INFOR424.
- S. Puertas-Martín, A. J. Banegas-Luna, M.
Paredes-Ramos, J. L. Redondo, P. M. Ortigosa, O. O. Brovarets’, and H.
Pérez-Sánchez, “Is high performance computing a requirement for novel drug discovery
and how will this impact academic efforts?” Expert Opinion on Drug Discovery, vol.
15, no. 9, pp. 981–986, 2020, issn: 1746045X. doi: 10.1080/17460441.2020.1758664.
[Online]. Available: https://doi.org/10.1080/
17460441.2020.1758664.
- S. Puertas-Martín, J. L. Redondo, P. M.
Ortigosa, and H. Pérez-Sánchez, “OptiPharm: An evolutionary algorithm to compare
shape similarity,” Scientific Reports, vol. 9, no. 1, p. 1398, Dec. 2019, issn:
2045-2322. doi: 10.1038/s41598-018-37908-6. [Online]. Available:
http://www.nature.com/articles/s41598-018-37908-6.
- A. J. Banegas-Luna, J.
P. Cerón-Carrasco, S. Puertas-Martín, and H.
Pérez-Sánchez, “BRUSELAS: HPC Generic and Customizable Software Architecture for 3D
Ligand-Based Virtual Screening of Large Molecular Databases,” Journal of Chemical
Information and Modeling, vol. 59, no. 6, pp. 2805–2817, Jun. 2019, issn:
1549-9596. doi: 10.1021/acs.jcim.9b00279. [Online]. Available: https://pubs.acs.org/doi/101021/acs.jcim.9b00279.
.
- M. R. Ferrández, S. Puertas-Martín, J. L. Redondo, B. Ivorra, A.
M. Ramos, and P. M. Ortigosa, “Highperformance computing for the optimization of
high-pressure thermal treatments in food industry,” The Journal of Supercomputing,
vol. 75, no. 3, pp. 1187–1202, Mar. 2019, issn: 0920-8542. doi:
10.1007/s11227018-2351-4. [Online]. Available: http://link.springer.com/10.1007/s11227-018-2351-4.
International Conferences
- S. Puertas-Martín, J. L. Redondo, H. Pérez-Sánchez, V. J. Gillet, and P. M. Ortigosa, “Optimization based
on atom-pair properties in flexible ligands by optipharm,” in XV. Workshop on Global Optimization, Uni-
versity of Szeged, Szeged, Hungary, Sep. 2022.
- J. J. Moreno, S. Puertas-Martín, J. L. Redondo, L. G. Casado, P. M. Ortigosa, and E. M. Garzón, “A new
hybrid optimization algorithm to combine physical and biological criteria to compute imrt planning,” in
19th Workshop on Advances in Continuous Optimization, University Nova de Lisboa, Lisbon, Portugal, Jul.
2022.
- J. J. Moreno, S. Puertas-Martín, J. L. Redondo, P. M. Ortigosa, and E. M. Garzón, “Acceleration of the
tuning of eud model for imrt planning on multigpu clusters,” in 22th International Conference Computa-
tional and Mathematical Methods in Science and Engineering, University of Cadiz, Rota, Spain, Jul. 2022.
- S. Puertas-Martín, J. L. Redondo, A. J. Banegas-Luna, E. M. Garzón, H. Pérez-Sánchez, V. J. Gillet, and
P. M. Ortigosa, “Virtual screening based on electrostatic similarity and flexible ligands,” in The 22nd In-
ternational Conference on Computational Science and Its Applications, University of Malaga, Malaga, Spain,
Jul. 2022.
- S. Puertas-Martín, J. L. Redondo, V. J. Gillet, H. Pérez-Sánchez, and P. M. Ortigosa, “Optimization
method for maximizing the similarity in flexible molecules,” in 19th Workshop on Advances in Contin-
uous Optimization, University Nova de Lisboa, Lisbon, Portugal, Jul. 2022.
- S. Puertas-Martín, J. J. Moreno, J. L. Redondo, P. M. Ortigosa, A. Zawadzka, J. Miroforidis, I. Kaliszewski,
and E. M. Garzón, “New multiobjective strategies to optimize constrained eud radiotherapy models,” in 26th International Conference on Multiple Criteria Decision Making, University of Portsmouth, Portsmouth,
United Kingdom, Jun. 2022.
- S. Puertas-Martín, J. L. Redondo, E. M. Garzón, H. Pérez-Sánchez, and P. M. Ortigosa, “Increasing
the accuracy of optipharm’s virtual screening predictions by implementing molecular flexibility,” 9th
International Work-Conference on Bioinformatics and Biomedical Engineering, University of Granada, Gran
Canaria, Spain, Jun. 2022
- S. Puertas-Martín, J. J. Moreno, J. L. Redondo,
P. M. Ortigosa, and E. M. Garzón, “Optimizing eud model parameters in radiotherapy
planning,” in The 7th Int’l Conf on Health Informatics and Medical Systems, American
Council on Science and Education, Las Vegas, USA, Jul. 2021.
- S. Puertas-Martín, J. L. Redondo, H.
Pérez-Sánchez, and P. M. Ortigosa, “Optimization of molecular descriptors using
memetic algorithms,” in 18th Workshop on Advances in Continuous Optimization,
EurOpt2021, Ecole Nationale de l’Aviation Civile, Toulouse, France, Jul. 2021.
- S. Puertas-Martín, J. L. Redondo, H.
Pérez-Sánchez, and P. M. Ortigosa, “Maximizing the electrostatic similarity in drug
discovery through evolutionary algorithms,” in 8th International Work-Conference on
Bioinformatics and Biomedical Engineering, University of Granada, Granada, Spain,
Sep. 2020.
- S. Puertas-Martín, J. L. Redondo, H.
Pérez-Sánchez, and P. M. Ortigosa, “Virtual screening in electrostatic potential
using an evolutionary algorithm,” in Proceedings of META18: 7th International
Conference on Metaheuristics and Nature Inspired Computing, Université de Lille,
Marrakech, Morocco, Oct. 2018, pp. 207–209.
- S. Puertas-Martín, J. L. Redondo, H.
Pérez-Sánchez, and P. M. Ortigosa, “Multi-objective evolutionary algorithm for
evaluation of shape and electrostatic similarity,” in Proceedings of LeGO 2018 -
Int. Workshop on Global Optimization. AIP Conference Proceedings, Leiden University,
vol. 1, Sep. 2018, pp. 1–4, isbn: 9780735417984. doi: 10.1063/1.5089986. [Online].
Available: http://aip.scitation.org/doi/abs/10.1063/1.5089986.
- S. Puertas-Martín, J. L. Redondo, H.
Pérez-Sánchez, and P. M. Ortigosa, “Optimizing electrostatic similarity using a
global evolutionary algorithm,” in Proceedings of 6th EUROPT Workshop on Advances in
Continuous Optimization, University of Almería, Almería, Spain, Jul. 2018.
- S. Puertas-Martín, J. L. Redondo, H.
Pérez-Sánchez, and P. M. Ortigosa, “Virtual screening in molecular shape by using an
evolutionary algorithm,” in Proceedings OLA’2018 International Workshop on
Optimization and Learning: Challenges and Applications, Université de Lille,
Alicante, Spain, Feb. 2018, pp. 63–64.
- M. R. Ferrández, S. Puertas-Martín, J. L. Redondo, B. Ivorra, R.
A. M, and O. P. M, “High-performance computing for optimizing high-pressure thermal
treatments in food processing,” in Proceedings of the 17th International Conference
on Computational and Mathematical Methods in Science and Engineering, CMMSE 2017,
University of Cadiz, Alicante, Spain, Jul. 2017, pp. 862–869, isbn:
978-84-617-8694-7.
- S. Puertas-Martín, M. R. Ferrández, J. L.
Redondo, H. Pérez-Sánchez, and P. M. Ortigosa, “Enhancing molecular shape comparison
by a parallel global evolutionary algorithm,” in Proceedings of the 17th
International Conference on Computational and Mathematical Methods in Science and
Engineering, CMMSE 2017, University of Cadiz, Rota, Spain, Jul. 2017, pp. 1722–1728,
isbn: 978-84-617-8694-7.
- S. Puertas-Martín, H. den-Haan, J. L. Redondo,
H. Pérez-Sánchez, and P. M. Ortigosa, “Enhancing molecular shape comparison by a
global evolutionary algorithm,” in 4th International Work-Conference on
Bioinformatics and Biomedical Engineering, University of Granada, Granada, Spain,
2016.
- S. Puertas-Martín, J. L. Redondo, H. den-Haan,
H. Pérez-Sánchez, and P. M. Ortigosa, “Multi-objective based scoring function for
ligand based virtual screening,” in Proceedings of the XIII Global Optimization
Workshop, University of Minho, Braga, Portugal, 2016, isbn: 978-989-20-6764-3.
Educational Conferences
- J. J. Moreno, S. Puertas-Martín, F. Orts, N. C. Cruz, J. L.
Redondo, E. Garzón, and O. P. M., “On simulating an arm processor for teaching
computer structure,” in 12th annual International Conference of Education, Research
and Innovation (ICERI 2019), Seville, Spain, Dec. 2019.
- F. Orts, N. C. Cruz,
S. Puertas-Martín, M. Ruiz-Ferrández, J. J.
Moreno, C. Medina-López, P. M. Ortigosa, V. Ruíz, L. Casado, J. M. Salmerón, J. L.
Redondo, G. E. Garzón, G. Ortega, and R. Villegas, “Learning quantum computation
through simple examples,” in 11th International Conference of Education, Research
and Innovation (ICERI 2019), Seville, Spain, Dec. 2019.
- F. Orts, N. C. Cruz,
S. Puertas-Martín, M. Ruiz-Ferrández, J. J.
Moreno, C. Medina-López, P. M. Ortigosa, V. Ruíz, L. Casado, J. M. Salmerón, J. L.
Redondo, G. E. Garzón, G. Ortega, and R. Villegas, “Learning quantum computation
through simple examples,” in 11th International Conference of Education, Research
and Innovation (ICERI 2019), Seville, Spain, Dec. 2019.
- N. C. Cruz, M. R.
Ferrández, E. M. Garzón, J. M. García Salmerón, L. González Casado, V. González
Ruiz, C. Medina-López, J. J. Moreno, G. Ortega López, P. M. Ortigosa, F. J. Orts,
S. Puertas-Martín, J. L. Redondo, J. F.
Sanjuan Estrada, and T. Santamaría López, “Simulación de un procesador arm para la
enseñanza de estructura de computadores. poster,” in Jornadas de Innovación Docente
y Experiencias Profesionales en la Universidad de Almería. Curso 2019-20,
Vicerrectorado de Enseñanzas Oficiales y Formación Continua y por la Coordinación de
Gobierno e Interacción con la Sociedad y las Empresas de la Universidad de Almería,
Almería, Spain, Sep. 2019.
- S. Puertas-Martín, J. J. Moreno, F. J. Orts, N.
C. Cruz, J. L. Redondo, E. M. Garzón, and P. M. Ortigosa, “Simulación de un
procesador arm para la enseñanza de estructura de computadores,” in Actas de las
Jornadas SARTECO 2019, Cáceres, Spain, Sep. 2019, pp. 235–240, isbn:
978-84-09-12127-4.
- V. González-Ruiz, G.
Ortega, E. Garzón, N. Calvo-Cruz, R. J. L., J. Salmerón, L. Casado, P. M. Ortigosa,
C. Medina-López, J. J. Moreno, M. R. Ferrández, F. Orts, S. Puertas-Martín, and T. Santamaría-López,
“Project-based learning: An experience,” in 11th International Conference on
Education and New Learning Technologies (EDULEARN 2019), Palma, Spain, Jul. 2019.
- N. C. Cruz, M. R.
Ferrández, E. M. Garzón, J. M. García Salmerón, L. González Casado, V. González
Ruiz, C. Medina-López, J. J. Moreno, G. Ortega López, P. M. Ortigosa, F. J. Orts,
S. Puertas-Martín, J. L. Redondo, J. F.
Sanjuan Estrada, T. Santamaría López, and R. Villegas, “Recursos para el aprendizaje
de computación cuántica en el grado de ingeniería informática. poster,” in Jornadas
de Innovación Docente y Experiencias Profesionales en la Universidad de Almería.
Curso 2018-19, Vicerrectorado de Enseñanzas Oficiales y Formación Continua y por la
Coordinación de Gobierno e Interacción con la Sociedad y las Empresas de la
Universidad de Almería, Almería, Spain, Sep. 2018.
National Conferences
- M. R. Ferrández, S. Puertas-Martín, J. L. Redondo, B. Ivorra, A.
M. Ramos, and P. M. Ortigosa, “Computación de alto rendimiento para optimizar
tratamientos térmicos de alta presión en la industria alimenticia,” in Avances en
arquitectura y tecnología de computadores. Actas de las Jornadas SARTECO 2017,
Málaga, Spain, Sep. 2017, pp. 119–122, isbn: 978-84-697-4835-0.
- S. Puertas-Martín, M. R. Ferrández, J. L.
Redondo, H. Pérez-Sánchez, and P. M. Ortigosa, “Cribado virtual mediante un
algoritmo evolutivo global paralelo,” in Actas de las Jornadas SARTECO 2017,
Cácares, Spain, Sep. 2017, pp. 177–179, isbn: 978-84-697-4835-0.
- S. Puertas-Martín, M. R. Ferrández, J. L.
Redondo, H. Pérez-Sánchez, and P. M. Ortigosa, “Algoritmo evolutivo global como
herramienta de cribado virtual utilizando la forma molecular,” in III Jornadas
Doctorales de la Universidad de Murcia, Murcia, Spain, May 2017, pp. 236–240, isbn:
978-84-608-9779-8.
Patents and Intellectual Properties
OPTIPHARM: an innovative evolutionary algorithm for virtual screening 2018
P. M. Ortigosa, J. L. Redondo, S. Puertas-Martín
and H. Pérez-Sánchez.
- University of Almería and Universidad
Católica San Antonio de Murcia.
- Application Number: 201899900606752.
Register number: RTA-94-18.
- Registration Date: 16/02/2018. Concession
date: 09/08/2018.
Research Stays
Predoctoral Stay, 10.09.2018-10.12.2018
Centre for Logistics and Heuristic Optimization (CLHO), Kent Business School, University
of Kent. Canterbury, CT2 7NZ, United Kingdom
Projects
Soluciones de Alto Rendimiento para retos actuales de la computación
cientí ca (HPC4Sci) (High Performance Solutions for Today’s Scienti c
Computing Challenges (HPC4Sci)). 01.01.2019 – 31.12.2021
National project.
- Principal Research: Pilar Martínez
Ortigosa and Gracia Ester Martín Garzón.
- Number of researchers: 31.
- Code: RTI2018-095993-B-100.
- Funding: Spanish Ministry of Science and
Innovation. National Program for
Scienti c Research, Development and Technological Innovation
- Total amount: 186.461,00 Euros
Computación de Altas Prestaciones para Optimizar Plani caciones de
Radioterapia de IntensidadModulada (High Performance Computing to
Optimize IntensityModulated Radiation Therapy Planning). 15.10.2019 –
14.10.2021
Regional project.
- Principal Research: Ester Martín Garzón
and Juana López Redondo.
- Number of researchers: 14.
- Code: UAL18-TIC-A020-B.
- Funding: Junta de Andalucia, Fondos
Feder UAL.
- Total amount: 76.800,00 Euros.
Descubrimiento y optimización de compuestos bioactivos mediante
técnicas avanzadas de química computacional (Discovery and optimization
of bioactive compounds through advanced computational chemistry
techniques).01.01.2019 – 31.12.2019
Regional project.
- Principal Research: Horacio Emilio Pérez
Sánchez.
- Number of researchers: 12.
- Code: 20988/PI/18.
- Funding: Fundación Séneca.
- Total amount: 62.000 Euros.
Metodologías computacionales para desafíos de la sociedad (Computational
methodologies for societal challenges). 01.01.2016 – 31.12.2019
National project.
- Principal Research: Leocadio González
Casado and Pilar Martínez Ortigosa.
- Number of researchers: 21.
- Code: TIN2015-66680-C2-1-R.
- Funding: Spanish Ministry of Economy and
Competitiveness.
- Total amount: 147.620 Euros.
Teaching Innovation Projects
Desarrollo de Recursos para motivar el estudio de la Ingeniería de Computadores
(Development
of Resources to motivate the study of Computer Engineering). 2019
Convocatoria de Grupos Docentes para la Creación de Materiales Didácticos en la
Universidad
de Almería. Bienio 2018 y 2019 (Call for Teaching Groups for the Creation of
Didactic Materials
at the University of Almeria. Biennial 2018 and 2019)
- Funding: University of Almería.
- Total amount: 800 Euros.
Desarrollo de Recursos para motivar el estudio de la Ingeniería de Computadores
(Development
of Resources to motivate the study of Computer Engineering).2018
Convocatoria de Grupos Docentes para la Creación de Materiales Didácticos en la
Universidad
de Almería. Bienio 2018 y 2019 (Call for Teaching Groups for the Creation of
Didactic Materials
at the University of Almeria. Biennial 2018 and 2019)
- Funding: University of Almería.
- Total amount: 800 Euros.
Teaching
Degree in Informatics 2019-2020
University of Almería, Spain
- Network access technologies. Third year.
41 hours.
- Peripherals and interfaces. Third year.
19 hours.
- Quality Assurance System of the University of
Almeria. Academic quality 4.72 out of 5.
Degree in Informatics 2018-2019
University of Almería, Spain
- Structure and computer technology. First
year. 38 hours
- Network access technologies. Third year.
19 hours
- Quality Assurance System of the University of
Almeria. Academic quality 4.65 out of 5.
Degree in Informatics 2017-2018
University of Almería, Spain
- Peripherals and interfaces. Third year.
19 hours.
- Network access technologies. Third year.
19 hours.
- Multi-processorss. Third year. 18 hours.
- Structure and computer technology. First
year. 2 hours
- Quality Assurance System of the University of
Almeria. Academic quality 4.82 out of 5.
Final Project Supervisor
Degree in Informatics, 2020-2021
University of Almería, Spain.
- Co-supervisor in a Final Degree Project:
Arti cial vision-based fall recognition (Reconocimiento
de caídas con Visión Arti cial)
- Co-supervisor in a Final Degree Project:
Gesture control monitoring (Monitorización
mediante control gestual)
Degree in Informatics, 2019-2020
University of Almería, Spain.
- Co-supervisor in a Final Degree Project:
SMARTFRIDGE: Recognition of Actions in a
Refrigerator and Decision Making in a Smart Enviroment. Award: Best Final degree
project.
Skills
Languages
C, C++, JAVA, Python, LATEX.
Parallel Programming
Paradigms
MPI, PThreads.
Software applied
to drug discovery
OpenEye’s Software (ROCS, EON, VIDA, OMEGA), OpenEye’s Toolkit, Pymol, Reflex3D,
WEGA, OptiPharm